Overview
The PiezoSleep Mouse Behavioral Tracking System is a complete solution for labs and researchers looking to monitor and analyze data regarding sleep/wake cycles in rodents. This system is cost effective and totally non-invasive. Automated sleep-wake scoring reduces costs and non-surgical methods saves time and allows for researchers to move forward in studies.
How?
•Our Sleep Wake monitoring system is based on piezoelectric sensor technology.
•Our Piezoelectric polymer film transforms mechanical pressure into electrical signals.
•We have attained a sleep/wake classification accuracy of over 90%  (based on validation with simultaneous EEG/EMG and piezo recording).
•Extremely High throughput.
•Non invasive! Overcomes the surgical, recovery and cost limitations of EEG/EMG.
Additionally, the PiezoSleep Mouse Behavioral Tracking System is flexible and scalable. Complete systems are designed to easily be scaled according to budget and project needs.
Increase the statistical power of your behavior based research simply by adding additional cages.  Yes, It’s that simple!
Usage
Our Breakthrough Technology: The PiezoSleep Mouse Behavior Tracking System provides a non-surgical, non-invasive, fully automated system for high throughput studies of sleep and wake in research animals. Our cost-effective integrated sensors, hardware and software provide continuous and real-time scoring of sleep and wake over days, weeks or months.
System Details
Hardware
The PiezoSleep Mouse Behavioral Tracking System is a comprehensive and turn-key sleep/wake behavioral tracking platform. An entry-level set includes:
- Customized Open-Floor Cages
- Non-invasive PizeoFloor Sensors (PZ-77)
- Cage Amplifiers [based on cage quantity] (PZ-100)
- Data Acquisition Sensors (DAQ)
- Operations manual/instruction
The system, when integrated, provides proven accurate sleep/wake analysis in lab animals, and eliminates the need for human scoring. The piezoelectric floor pads in cages provide a non-invasive alternative to monitor and test mice during sleep, upon wake and throughout “normal” sleep activity.
Cages can be customized to suit a variety of needs and can accommodate differential feeding, watering, stimulus adapters, etc. Each individual cage and complete system is thoroughly tested and comes calibrated to suit your project needs.
Software
The PiezoSleep Mouse Behavioral Tracking System comes standard with feature-rich software to visualize sleep-wake behavior in mice. The data collection process is continuous, and scores automatically while the system is running. When a collection is complete, users can purchase SleepStats Data Explorer to visualize the collected data and create custom reports.
PiezoSleep Mouse Behavioral Tracking System was designed with most users in mind, however, if your team requires a customized solution, we can assist you from initial design and consultation to final product. Contact us for more information.
*Signal Solutions provides ongoing service contracts for analyzing data collected through a PiezoSleep Mouse Behavioral Tracking System. This data is collected and analyzed through SleepStats Data Explorer and Signal Solutions PiezoCloud services.
The PiezoSleep Mouse Behavioral Tracking System features programs that open and process multi-channel files created by the high-throughput PiezoSleep data recording and real-time monitoring system.
- The programs in this toolbox perform the following functions:
- Plotting graphical descriptions of sleep and wake behavior
- Reprocessing sensor data to create feature vectors
- Manipulating data files
Abnormal Sleep Phenotypes Identified With PiezoSleep Mouse Behavioral Tracking System
View full data from IMPC: Gene variants with abnormal sleep behavior discovered using PiezoSleep System
System Users
The Sleep-Wake Behavior Tracking System has been deployed in multiple sleep phenotyping efforts in mice, including:
- école supérieure de physique et de chimie industrielles de la ville de Paris (ESPCI Paris Tech)
- Helmholtz Zentrum München (The German Mouse Clinic)
- Oak Ridge National Laboratory
- Oxford University
- Smith College
- SRI International
- Stanford University
- The Jackson Laboratory
- University of Lausanne
- University of Pittsburgh
- University of Tennessee Health Sciences Center
- University of Texas Health Science Center, Houston
- Washington State University
- Weill Medical College of Cornell University
- Western Kentucky University
- Yale
